Cytolytic mechanisms required for virus elimination.

Funding Activity

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Funded Activity Summary

Viruses provoke devastating disease. The immune system kills cells that are infected with viruses. To do this, immune cells release granules that are packaged with different killer molecules. It is unknown which killer molecules participate over the course of an immune response to virus. Here, we will investigate this process for cells that are infected with influenza A virus and herpes simplex virus. This study will allow the design of strategies to limit widespread damage inflicted by viruses.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $698,567.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

NK cells | cell-mediated cytotoxicity | cytotoxic T cells | granzyme | herpes simplex virus | immunity to infection | influenza | vaccine | viral immunity