Evaluation of immune correlates for virus-specific CD8+ T cells following prime-boost vaccination

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/508902

Funding Status
Closed

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Funded Activity Summary

This project will use cutting-edge technology to evaluate the quality of virus-specific white blood cells generated following vaccination. Clinically relevant vaccination strategies will be analysed in a well characterised mouse model of infection to produce correlates associated with protective vaccine efficacy, particularly in an immunosupressed setting. This will lead to more focused research and ultimately the development of prophylactic and therapeutic HIV vaccines.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $397,889.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

HIV vaccines | HIV-AIDS | T cell immunity | cell mediated immunity | cell-mediated immunity | cytotoxic T cells | development of immunological memory | immunologic memory | vaccine development

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