Novel insights into the mechanisms of how viruses cause arthritis-arthralgia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/508600

Funding Status
Closed

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Funded Activity Summary

Many viruses are known to cause arthritis (e.g. HIV, hepatitis viruses, mosquito borne viruses). Symptoms of viral arthritis include joint pain, stiffness, and swelling. The mechanism of disease is poorly understood. We have developed a novel animal model of disease by which to study arthritic disease caused by viral infections. This model provides an excellent opportunity to explore the mechanisms of rheumatic disease in a complete functioning animal and to explore new treatment regimes.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: NHMRC Project Grants

Funding Amount: $626,459.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alphaviruses (Ross River virus) | Arthralgia | Complement proteins | Cytokines and chemokines | Epidemic polyarthritis | Inflammation | Myositis (muscle inflammation) | Ross River virus disease | Viral arthritis

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