Mechanisms underlying the effects of retinoic acid receptor gamma in haemopoiesis and bone homeostasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/502625

Funding Status
Closed

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Funded Activity Summary

My recent studies have demonstrated that a model of vitamin A deficiency results in impaired blood cell production and contributes to a blood cell disorder that can progress to leukaemia. There are also reduced numbers of blood stem cells (which give rise to all blood cells) and bone (which helps to regulate blood cell production) in this mouse model. In these studies I seek to understand more on how vitamin A deficiency causes these defects, which may lead to better treatment of such diseases.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: Career Development Fellowships

Funding Amount: $366,801.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone | haemopoiesis | haemopoietic stem cells | retinoic acid receptors

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