Apoptotic pathways in pancreatic beta cells leading to type 1 diabetes and transplant rejection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/502605

Funding Status
Closed

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Funded Activity Summary

The destruction of insulin-producing beta cells in the pancreas by immune cells leads to the need for daily insulin injections in patients with type 1 diabetes. This project aims to understand how beta cells are destroyed. A knowledge of the process by which this occurs will indicate ways we can protect these cells. Our previous work has suggested strategies that may protect beta cells, and we aim to test these. Such protection may eventually allow beta cell replacement by transplantation.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $535,333.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Emergency medicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Autoimmunity | Islet Transplantation | NOD mouse | Type 1 Diabetes | apoptosis | cytotoxic T cell | pancreatic beta cell | type 1 diabetes

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