Identification of telomere-specific recombination pathways

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/502600

Funding Status
Closed

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Funded Activity Summary

Human cells stop to grow when the natural ends of chromosomes become too short. One way of how cancer cells evade this growth arrest is by using a copy-mechanism to extend short chromosome ends. Ironically, this copy mechanism is usually used by cells to keep the structure of chromosomes intact in order to prevent mutations that cause cancer. Here we will study a novel protein that contributes to the copy mechanism at short chromosome ends, but not as much in normal mutation prevention.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $540,075.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Meiosis And Recombination

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | cancer biology | cancer therapy | fungal genetics | genetics | molecular basis of disease | molecular genetics | telomeres | tumourigenesis

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