Studies of metabolites of synthetic flavonols for the treatment of cardiovascular disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/499312

Funding Status
Closed

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Funded Activity Summary

Cardiovascular disease, including heart attack and stroke, is the leading killer of Australians. A promising new drug, NP202, can reduce the amount of tissue damaged from a heart attack; however, its mechanism of action remains obscure. NP202 is metabolized to a range of compounds, one of which is partly responsible for its beneficial effects. In this project we will identify other metabolites of NP202 and characterize their biological activity to gain insight into its mechanism of action.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2009

Funding Scheme: NHMRC Development Grants

Funding Amount: $207,440.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry - carbohydrates

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acute myocardial infarction | antioxidant activity | coronary heart disease | drug | flavonol | organic chemistry | reperfusion injury | vascular activity

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