The Role of Paneth Cells in Ileal Crohns Disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/498405

Funding Status
Closed

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Funded Activity Summary

Crohn's disease is a severe, chronic inflammatory disease of the gut which affects up to 50,000 Australians. The majority of patients develop the disease in their twenties, with significant impact on their quality of life. Our preliminary work has identified a novel gene, which could potentially cause a critical reduction in the production of anti-bacterial proteins by cells in the small bowel. Exploring the function of this gene in relation to clinical outcome could lead to better treatment.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $229,744.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sport and exercise nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bacterial pathogen | Bacterial pathogens | Crohn's disease | Differential gene expression | Identification of genes leading to disease | Inflammatory bowel disease | Molecular genetics | Mucosal inflammation

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