Evaluation of the therapeutic potential of SFTI-FCQR, a novel kallikrein 4-specific protease inhibitor

Funding Activity

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Funded Activity Summary

Prostate and ovarian cancers are on the rise in Australia's ageing population. In previous work, we have studied prostate and ovarian cancer cells that we have engineered to make the protease KLK4. These cells show signs associated with aggressive tumours and in particular may have some of the changes found in cancer cells that spread from their site of origin (metastasize). In this project, we will look at a drug-like molecule that we have designed with the aim of blocking the activity of KLK4.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Development Grants

Funding Amount: $167,303.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutritional science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drug design | Invasion and Metastasis | Kallikrein KLK4 | Ovarian cancer | Peptides | Prostate cancer | Protease inhibitors