Defining the genetic and epigenetic targets involved in serrated neoplasia of the colorectum

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/496626

Funding Status
Closed

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Funded Activity Summary

We believe that some colon cancers develop from a type of polyp called a hyperplastic polyp and that many of these polyps contain a specific mutation in a gene called BRAF. We are conducting tumour studies using mouse models that carry different mutated genes to understand their role and importance in the pathway by which these cancer evolve. Understanding this will allows us to develop better treatments for pateints suffering from colon cancer.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $324,122.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer biology | colon cancer | colorectal cancer | methylation | oncogene | transgenesis | tumorigenesis

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