Proteomics of arthritis: Exploring mechanisms of cartilage degradation and biomarker identification

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/491237

Funding Status
Closed

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Funded Activity Summary

Arthritis is a major clinical and socio-economic problem. Arthritis involves the destruction of cartilage in joints. However, the mechanisms of initiation and progression of cartilage destruction remain poorly understood. Our studies will use new proteomic approaches to identify the changes in protein synthesis and degradation in mouse models of arthritis. This will provide critical information on disease mechanisms and for the development of diagnostic biomarkers and therapeutic approaches

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $592,034.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Orthopaedics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arthritis | cartilage | cartilage damage | cartilage degeneration | extracellular matrix | osteoarthritis | proteomics | rheumatoid arthritis

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