A multi-site RCT comparing spinal and general anaesthesia on neurodevelopmental outcome and apnoea in infants

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/491226

Funding Status
Closed

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Funded Activity Summary

5% of Australian children have surgery when they are infants. Recent studies have shown that surgery in babies is associated with poorer neurological outcomes. The reason for this is unclear but animal experiments suggest it may be due to some anaesthetic agents. This trial will determine if the anaesthetic is the cause of the problem. 660 babies who need surgery will be randomised to receive a general or local anaesthetic, and then followed for 5 years.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $512,072.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Anaesthesia | Anaesthesia and cognitive deficit | Apnoea of infancy | Developmental neurobiology | Infantile apnoea | Neonatal brain injury | Neurotoxicity | Neurotoxicity- damage to nervous system caused by drugs | Randomised controlled trial

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