Modulation of HIV-1 latency in primary CD4 T cells by chemokines and dendritic cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/491154

Funding Status
Closed

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Funded Activity Summary

Although treatment of HIV using antiretroviral drugs has dramatically improved outcome the presence of latent infection in long lived T cells has so far prevented cure of HIV infection. This study examines the roles of chemokines (proteins that control cell migration) and a special type of infection fighting cell, the dendritic cell, in generating latent infection in resting T cells. These studies could potentially identify new ways to treat and potentially cure HIV infection.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $380,167.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Chemokines | Dendritic cells | Evasion of immune system | HIV-AIDS | Human Immunodeficiency virus infection | Immunological intervention | T lymphocytes | retroviral infection

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