A fluorescent zebrafish model of endodermal cell migration.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/491087

Funding Status
Closed

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Funded Activity Summary

The most catastrophic event in cancer progression is when individual cancer cells move to other areas of the body and develop into secondary tumours. This very complex process shows striking similarities to cell movements during embryogenesis. In this project, we use a model system, the zebrafish, to analyse how cells move during embryogenesis. We will determine the genes required for cell movements in the zebrafish embryo, so we can find the corresponding genes in human cancers.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $535,333.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer: mechanisms of growth, invasion, metastases | cell adhesion | cell migration | colorectal cancer (CRC) | endoderm development | epithelial morphogenesis | tumour metastasis | tumour metastasis and invasion

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