Receptor-mediated Actions of Prorenin in Diabetic Retinopathy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/491058

Funding Status
Closed

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Funded Activity Summary

Despite improvements in patient care, the incidence of diabetic retinopathy is dramatically increasing. Recent evidence suggests that a component of a hormonal system, called prorenin, may participate in the development of diabetic organ disease. We will evaluate the role of prorenin in vascular and nerve damage in animal models of diabetic retinopathy. We will determine if a new inhibitor of prorenin, prevents retinal injury and is a potential treatment for diabetic retinopathy.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $733,841.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Opthalmology And Vision Science

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetes | diabetes complications | diabetic retinopathy | microvascular | neuron-glia interactions | renin angiotensin system | retina | retinopathy, blindness

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