Predicting the substrate specificity of proteases

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/490989

Funding Status
Closed

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Funded Activity Summary

Proteases are enzymes that degrade other proteins. These molecules are essential for life and drive fundamental processes such as blood clotting and the inflammatory response. Protease dysfunction underlies numerous human diseases, including cancer. This proposal aims to investigate whether structural information can be used to improve our ability to accurately predict the target specificity of proteases.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2012

Funding Scheme: Early Career Fellowships

Funding Amount: $291,309.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bioinformatic approach | human protease systems biology | substrate specificity prediction | therapeutics target

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