Dissecting mechanisms of generalised immune activation and cellular dysfunction in HIV infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/490988

Funding Status
Closed

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Funded Activity Summary

How HIV infection compromises the host immune system is still not well understood. We will study how HIV surface proteins contribute to heightened immune activation during chronic infection. This generalised activation eventually leads to dysfunctional cellular immune responses and loss of partial control of infection. We will additionally investigate the extent and impact of the loss of functional immune responses in chronic HIV infection.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2014

Funding Scheme: Early Career Fellowships

Funding Amount: $422,576.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

HIV-AIDS | T lymphocytes | Viral immunology

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