How does basal chromatic structure predict cytokine gene responses?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/490014

Funding Status
Closed

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Funded Activity Summary

To recognise foreign pathogens and eradicate them from the body, immune cells need to quickly switch on genes encoding factors which communicate between cells and drive the immune response. Incorrect expression of these genes contributes to immune diseases such as asthma, arthritis and leukaemia. The aim of this project is to study how the DNA environment of immune genes controls their ability to be switched on and off, and how altering this environment leads to incorrect gene expression.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $521,961.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chromatin | chromatin structure | cytokine expression | gene regulation | immune regulation | immunity | inflammatory disease | transcription

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