Development of a novel mannan-based avian influenza vaccine

Funding Activity

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Funded Activity Summary

We have a sugar (mannan) that can be used to increase immune responses. We have found that mannan decreases the dose of inactivated virus needed for intranasal immunization. We will investigate if dose sparing is seen when given intramuscularly. This method will be first tried with the human flu virus and if successful will be tried with the bird flu virus. If the preparation can protect mice and ferrets from human or bird flu infection it could develop into a human vaccine against bird flu.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2009

Funding Scheme: NHMRC Development Grants

Funding Amount: $195,566.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other biomedical and clinical sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Infectious disease | Influenza | Mucosal immunity | Vaccination at mucosal surfaces | Vaccine