The role of Src family tyrosine kinases in inflammatory lung disease and cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/487910

Funding Status
Closed

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Funded Activity Summary

We aim to learn why some people develop COPD, a serious lung disease, and adenocarcinoma, a common fatal lung cancer. COPD is mostly caused by cigarette smoke which induces lung inflammation. Lung inflammation, which involves macrophage activation, is a major cancer risk. Macrophages can destroy lung tissue, and they may promote cancer development. We will study the role of Src kinases, which can regulate macrophage activation, which may lead to new treatments for these diseases.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $535,333.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cigarette smoking | Inflammatory lung diseases | Inhibitory signaling | Lung cancer | Lyn tyrosine kinase | Macrophages | Mouse models of lung inflammation and cancer | Respiratory diseases

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