The Importance of p38 MAPK Signalling in Aging-Related Ischaemic Intolerance and Failed Cardioprotection

Funding Activity

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Funded Activity Summary

Ischaemic heart disease is the leading cause of death in Australia, and will rise in coming years with the aging of our population. Our research shows aged hearts become less resistant to damage during ischaemia-heart attack, and insensitive to normally beneficial therapies. This project will identify molecular changes responsible for these changes. By understanding how age impairs the hearts defences, it may be possible to improve therapy of ischaemic heart disease in older patients.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $496,302.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Ageing | Ageing Disease | Aging | Cardioprotection | Ischaemia-Reperfusion Injury | Ischaemic Heart Disease | MAP kinases | Myocardial Infarction | Myocardial Ischaemia