EGFR transactivation in cardiac hypertrophy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/472640

Funding Status
Closed

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Funded Activity Summary

Muscle cells that constitute the bulk of the human heart do not divide but enlarge as we grow. Accelerated heart cell growth, as a consequence of heart damage or other factors, is a predictor of heart failure and early death. This application examines the cellular events that control heart growth in response to angiotensin, a hormone linked to heart failure. By understanding the mechanism by which angiotensin promotes growth, better therapies against human cardiovascular disease will evolve.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $589,175.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nutrigenomics and personalised nutrition

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

EGF receptor transactivation | G-protein coupled receptors | angiotensin II receptors | cardiac hypertrophy | cardiovascular disease and hypertension | cell signalling | heart disease | molecular mechanisms

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