Pathogenic role of CDA1 via its profibrotic action in diabetic nephropathy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/472638

Funding Status
Closed

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Funded Activity Summary

We cloned a CDA1 several years ago and found that it played a major role in controlling a series of molecular events leading to production and accumulation of extracellular matrix causing scarring, as seen in diabetic nephropathy. This project aims to study the biological functions and molecular mechanisms of CDA1 in the context of diabetic nephropathy, hence allowing us to consider CDA1 as a molecular target for drug development to treat this condition and related complications.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $483,737.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology And Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

diabetic nephropathy | extracellular matrix | proliferation | renal diseases | renal interstitial fibrosis | renal interstitial scarring

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