KIT as a target for the modification of vascular proteoglycans and prevention of atherosclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/472611

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Heart disease occurs when arteries supplying blood to the heart become blocked. One aspect of this blockage is the capture of fats from the blood, by artery wall structures called proteoglycans. Proteoglycans are made up of a core protein and sugar chains (GAGs). The stickier the GAGs, the more fats that are captured. No drug treatment acts directly on the artery wall to prevent heart disease. This project aims to identify steps that lead to stickier GAGs and therefore a potential drug target.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $342,864.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical biochemistry and metabolomics not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | cardiovascular diseases | extracellular matrix | glycosaminoglycans | protein tyrosine kinase | proteoglycans | therapeutic target | vascular smooth muscle

Related Links