Role of IL-3 in allergic inflammation: modulation of basophils, mast cells, eosinophils and remodelling in asthma.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/471481

Funding Status
Closed

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Funded Activity Summary

Asthma is an important disease in the Australian community. We will investigate how the underlying inflammation in this disease is controlled and will focus our studies on a hormone-like regulator of the immune system called interleukin-3. Our hypothesis is that interleukin-3 regulates basophils, mast cells and remodelling of the airways which are central features of asthma. This study will give a better understanding of how the inflammation is caused and information for new drug targets.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2010

Funding Scheme: NHMRC Project Grants

Funding Amount: $495,380.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acute and chronic inflammation | airways inflammation | asthma | asthma and allergy | chronic inflammation | cytokines | inflammatory mediators | respiratory asthma

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