Communication between calcium ion channels in skeletal muscle excitation-contraction coupling

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/471418

Funding Status
Closed

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Funded Activity Summary

Ageing, injury, drugs or genetic defects cause muscle weakness, prevent exercise, compromise life style and contribute to poor health and osteoporosis. In order to move signals travel from our brain to muscles, where one calcium ion channel detects the signal and tells a second calcium channel to open and release calcium ions to initiate contraction. The project will pave the way for developing drugs to help with muscle disorders by trageting the site of interaction between the channels.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $603,100.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical mycology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Age-related and drug-induced myopthies | Calcium ion channels in skeletal muscle | Depolarisation-dependent calcium release from internal store | Dihydropyridine-receptor coupling to ryanodine receptor | Hereditary myopathy - malignant hyperthermia | Inactivity-induced osteoporosis | Neuromuscular disease | SPRY domain in ryanodine receptor | Skeletal muscle excitation-contraction coupling | Sports and accident-related muscle Injury

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