The role of glutathione transferase P1 in regulating allergic airways disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/471401

Funding Status
Closed

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Funded Activity Summary

Recent studies have shown that a single amino acid change in an enzyme called glutathione tranferase Pi (GSTP)1 protects against the likelihood of developing asthma. This enzyme is found in the cells that line the airways and detoxifies harmful chemicals such as those found in pollutants and cigarette smoke. The aim of our study is to understand how GSTP1 protects against the development of asthma.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $436,882.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Anaesthesiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway epithelium | airway function | airway hyperresponsiveness | airway remodelling | animal model | asthma | glutathione-S-transferases | oxidative stress

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