A polypill to prevent genome damage

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/464895

Funding Status
Closed

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Funded Activity Summary

It has become increasingly evident that damage to the genetic material in cells (DNA) is a fundamental initiating cause of cancer and accelerated ageing. Furthermore it has been shown recently that moderate deficiencies of certain vitamins and minerals can cause damage to DNA at a level that is observed for carcinogenic doses of radiation and toxic chemicals. In addition studies have shown that supplementation with certain vitamins resulted in a reduction of damage to DNA. The aims of this research is to determine whether daily intake of a pill containing certain vitamins and minerals causes a reduction in DNA damage in blood cells. The expected ultimate outcome is a cancer prevention strategy based on reducing the risk of damage to DNA.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2008

Funding Scheme: NHMRC Project Grants

Funding Amount: $407,033.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Preventive Medicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | carcinogenesis | complementary medicine | degenrative disease | genome damage | micronutrient deficiency | micronutrients | nutrigenomics

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