Virulence determinants of encephalitic flaviviruses

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/456126

Funding Status
Closed

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Funded Activity Summary

Murray Valley encephalitis, Japanese enecephaltis virus and West Nile virus are mosquito transmitted pathogens that cause severe and fatal neurological diseases in man and animals. Currenly, it is not clear why these viruses produce such severe diseases and therefore they are difficult to treat and prevent. In this project we will indentify the components of the viruses that allow them to invade the central nervous sytem and cause neurological symptoms. This will provide valuable information on critical elements of these pathogenic viruses that contribute to their virulence and will identify new candidate vaccines for prevention of the encephalitic diseases they cause.

Funded Activity Details

Start Date: 01-01-2008

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $455,670.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arbovirus diseases | encephalomyelitis | flavivirus | flavivirus encephalitis | immunisation | infectious diseases | molecular cloning | vaccine development | virulence

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