The role of Crim1 in growth factor activity and cell motility/adhesion.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/455972

Funding Status
Closed

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Funded Activity Summary

Crim1 is a novel protein which appears to regulate the activity of growth factors and therefore affects the normal development of a number of organs. It is particulrly involved in normal development of blood vessels. A greater understanding of how growth factor activity is modulated by Crim1 will have significance to almost every developmental and disease state involving such growth factors. The potential for Crim1 to link the activity of several distinct growth factor pathways may explain tissue specific differences in growth factor responses. These basic advances in understanding will have implications for many disease states, including renal disease, vascular disease and cancer.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $600,065.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiogenesis | cell biology | cell morphology | developmental genetics | ischaemia | kidney | regulation of tumour progression | renal dysplasia | tissue remodelling | vascular diseases

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