Defining the colonic abnormality underlying severe constipation and evaluating the efficacy of a novel treatment therapy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/455213

Funding Status
Closed

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Funded Activity Summary

This project aims to clarify the contractile patterns of the human colon which underlie the very common and distressing condition of constipation. We will be relating symptoms of constipation from a large number of sufferers with actual measurements of contractions along the colon in these patients. Furthermore by examining the in vivo colonic motor response to electrical stimulation of pelvic floor nerves, we will help to determine the potential of this new form of treatment for constipation. The aims of these projects will be to try and identify abnormal motor patterns responsible for constipation as well as determining a possible inductor of normal colonic motility so that future studies can target appropriate treatment at the responsible defect.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $487,990.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gastroenterology and Hepatology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Clinical research | Pacemaker | clinical diagnosis and assessment | colon | colonic dysmotiliy in adults | gastrointestinal manometry | motility disorder | pathophysiology | quality of life | slow transit constipation

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