Cognitive effects of adding ovarian function suppression to adjuvant hormonal therapy in premenopausal breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/454507

Funding Status
Closed

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Funded Activity Summary

There is mounting evidence that potentially curative treatment for breast cancer might, in some women, have an adverse effect on their subsequent cognitive function i.e. their memory and ability to think clearly. Thus it is important that when new treatments are being tested, the testing includes collecting information on the effect of the new treatment on a woman's cognitive function. There is currently an ongoing large international study examining whether suppressing ovarian function (and thus decreasing oestrogen levels) in women having treatment for breast cancer will improve their outcomes. However,it is known that oestrogen is important for normal cognitive functioning in premenopausal women so there is some concern that dropping the oestrogen levels in this way might cause impairment in cognitive function. In this sub-study we will compare the cognitive function of women having ovarian function suppression with those who do not, to determine if there are any differences. We will also examine how this might affect quality of life.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2011

Funding Scheme: NHMRC Project Grants

Funding Amount: $301,431.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology and Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | cognition | memory | ovarian function suppression | premenopausal women | women's health

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