The limb bud as a model for gubernacular migration during inguinoscrotal testicular descent.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/436913

Funding Status
Closed

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Funded Activity Summary

This project examines the mechanism of descent of the testes from its original position inside the abdomen of the fetus to the scrotum in baby boys. When this process is abnormal, it leads to the common anomaly of undescended testes. Tha ultimate aim is to understand the process well enough to consider nonoperative treatment. The study will look at the tip of the gubernaculum, the ligament that anchors the testis to the groin early in development, and how it develops a growing tip that elongates towards the scrotum. The project will examine the factors controlling this process as well as the embryological mechanism involved.

Funded Activity Details

Start Date: 01-01-2007

End Date: 01-01-2009

Funding Scheme: NHMRC Project Grants

Funding Amount: $439,073.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Paediatrics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

aetiology | calcitonin gene related peptide | cryptorchidism | gene expression | genitofemoral nerve and androgen | gubernaculum | inguinal hernia | limb-bud "progress-zone" | testicular descent

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