Genetic Dissection Of Stem Cell Function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/406676

Funding Status
Closed

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Funded Activity Summary

Adult and embryonic stem cells have enormous therapeutic potential. Haemopoietic stem cells have been the most intensely studied and widely used in a therapeutic setting, yet we have only a patchy knowledge of the genes required for their proliferation and survival. I will use classical genetic screens in the mouse to identify genes that regulate stem cell behaviour. I will analyse two existing mutant mouse strains with reduced numbers of haemopoietic stem cells, and execute a novel genetic screen utilising mice with a defect in the self-renewal of adult haemopoietic and neural stem cells, to find mice with a recovered stem cell compartment.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2009

Funding Scheme: Early Career Fellowships

Funding Amount: $276,750.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Cancer stem cells | Epigenetics | Haematopoiesis | Mutagenesis | Stem cells

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