Genomic and Proteomic Profiling of Dendritic Cell Heterogeneity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/406660

Funding Status
Closed

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Funded Activity Summary

Dendritic cells (DC) present antigens to T cells and regulate immunity and tolerance. DC are heterogeneous, comprising seven functionally distinct subsets. We will use genomics and proteomics to identify the plasma membrane and endosomal proteins that underpin this functional heterogeneity. Such proteins are potential targets for improved protocols of vaccination and prevention of autoimmunity. This project will thus provide further opportunities for high-quality research and commercialisation.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2010

Funding Scheme: NHMRC Strategic Awards

Funding Amount: $1,971,250.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

endosmal proteins | genomics and proteomics, plasma membrane | regulate immunity and tolerance.

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