Characterization of casein phosphopeptide amorphous calcium fluoride phosphate as a remineralization system

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/400299

Funding Status
Closed

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Funded Activity Summary

Dental caries (tooth decay) remains a major public health problem in Australia with an economic burden in excess of $1 billion p.a. The overall aim of this project is the development of a novel remineralizing agent (casein phosphopeptide stabilized amorphous calcium fluoride phosphate) for the remineralization of early tooth decay lesions (white spot lesions). The project will involve the testing of the ability of the novel remineralization system to remineralize (repair) white spot lesions in vitro and in situ. The project also involves the detailed characterization of the molecular interactions of the components of the remineralizing system using NMR spectroscopy and other techniques. It is anticipated that this project will result in the development of a system with substantialy superior properties for the non-invasive treatment (reversal) of white spot lesions and may ultimately lead to the development of a novel system for the treatment and prevention of tooth decay.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2008

Funding Scheme: NHMRC Project Grants

Funding Amount: $493,514.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Dentistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Calcium | Dental caries | Dental treatments | Fluoridation | Molecular mechanisms | Phosphoprotein | Prevention | Tissue regeneration | Tissue repair | Tooth erosion

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