Neurodegeneration in the ageing brain: how the pathways leading to aggregated protein cause disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/400202

Funding Status
Closed

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Funded Activity Summary

The team consists of eight highly experienced research scientists who are dedicated to solving the question of how the brain degenerates in the elderly when associated with the accumulation of certain proteins: e.g. A_ amyloid (Alzheimer�s disease) and PrP (Creutzfeldt-Jakob disease). Understanding the molecular pathways leading to the degeneration (loss of neuronal synapses) will permit the development of rational diagnostic and therapeutic interventions. Over the past five years the program has identified several diagnostic and therapeutic avenues which are now being developed by the Pharmaceutical and Biotechnology industries. Much more research is still required for maximizing the chances of success using these approaches.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2010

Funding Scheme: Programs

Funding Amount: $12,322,838.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer's disease | Amyloid | Creutzfeldt-Jacob disease | Motor neuron disease | Parkinson's disease

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