Understanding the mechanism and significance of CXCL16-mediated protection of tumour cells from CTL-induced apoptosis.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/399160

Funding Status
Closed

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Funded Activity Summary

This research will begin to determine the significance of changes in the amount of a recently-discovered protein on the surface of tumour cells. We have shown that an increase in expression of this protein protects tumour cells from destruction by our immune system's killer T cells. The outcome of this research could lead to a better understanding of how the immune system recognises and kills tumour cells, and ultimately, alternate vaccine strategies for tumours.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2008

Funding Scheme: NHMRC Project Grants

Funding Amount: $524,520.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Activation | CTL | Chemokine | Immunity | Lymphocyte | Tumour

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