Genome-wide combined linkage-association scan of multiply phenotyped twin sibships

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/389891

Funding Status
Closed

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Funded Activity Summary

We have a large ongoing study of adolescent twins, their siblings and parents who are multiply phenotyped in many domains including melanoma risk factors, serum biochemistry, and cognition. We used our first Medical Genomics grant to obtain a 5cM linkage scan for>500 families and have identified linkage peaks for many different phenotypes. To fine map these it will be most efficient to carry out a genome-wide association scan. We request funds to type a 500k SNP chip on 1000 individuals.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2009

Funding Scheme: NHMRC Strategic Awards

Funding Amount: $1,920,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Association | Complex diseases | Linkage | Statistical genetics | Twins

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