Regulation of 14-3-3 monomerisation controls cell life/death fate

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/379000

Funding Status
Closed

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Funded Activity Summary

14-3-3 proteins are becoming increasingly recognised as major multifunctional proteins that control key aspects of normal and pathological processes. Although initially viewed as inert components of signalling, we have now recognised for the first time that these are very dynamic proteins that can be regulated. Our main aim is to understand the regulatory mechanisms controlling the different dynamic forms of 14-3-3 and how each form in turn controls the process of life and death.

Funded Activity Details

Start Date: 01-01-2006

End Date: 01-01-2008

Funding Scheme: NHMRC Project Grants

Funding Amount: $524,770.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pathology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

14-3-3 proteins | cancer and related disorders | cancer biology | cell survival | pathology | protein kinase A | sphingolipid signalling

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