Development of novel vaccine strategies to prevent genital tract chlamydial infection

Funding Activity

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Funded Activity Summary

Genital tract chlamydial infection is the most common bacterial sexually transmitted disease world wide with 4-5 million cases occurring annually throughout the world. The incidence of chlamydial infection is increasing in the Australian population. The majority of infections in women are asymptomatic and, if untreated, go on to cause pelvic inflammatory disease, ectopic pregnancy and infertility. These conditions can be life threatening and are a significant public health cost. In the proposal we will develop novel vaccine strategies, involving both intranasal immunisation and immunisation by direct application to the skin, to induce protection against genital tract chlamydial infection. These studies will lay the basis for human trials of a vaccine to prevent what is now the most common STD in Australia. Such a vaccine to target this chronic infection would represent a major advance in preventive healthcare for the maintenance of good health.

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2007

Funding Scheme: NHMRC Project Grants

Funding Amount: $408,556.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Chlamydia | Chlamydial diseases | Infertility | Reproductive health | Reproductive immunology | Sexually transmitted infections | Vaccination immunology | Vaccines | Womens health