Effects of laterally wedged insoles on symptoms and disease progression in knee osteoarthritis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/350297

Funding Status
Closed

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Funded Activity Summary

Knee arthritis is a painful, disabling, costly condition particularly affecting the elderly. As there is presently no cure for knee arthritis, strategies that slow progression of the disease will reduce the personal and societal burden of arthritis. Most research has focussed on drug therapies, which are effective in reducing pain and disability but have side effects and are expensive. Insoles worn inside the shoes are a simple, cheap, self-administered intervention with the potential to slow disease progression in certain patients, in addition to managing symptoms. However, to date there has been little quality research investigating the effectiveness of insoles in knee arthritis. This study aims to see whether 12 months of wearing insoles can lead to improvements in knee pain and function and slow disease progression in 200 people with knee arthritis. It will use state-of-the-art technology, magnetic resonance imaging, to measure changes in the amount of knee cartilage. This research is timely and the findings will be of major significance as there is increasing world-wide attention on slowing progression of knee arthritis. Insoles are one of the few non-drug therapies with the potential to influence both symptoms and disease progression. If the results show that insoles are beneficial, then this research will: 1. Better inform clinical guidelines to firmly recommend insoles to manage knee arthritis 2. Provide the basis for developing education strategies for health care practitioners and patients about the benefits of insoles 3. Provide the impetus to make insoles more readily available directly to patients 4. Ultimately lead to better patient outcomes

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2008

Funding Scheme: NHMRC Project Grants

Funding Amount: $480,850.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Clinical trials | Knee cartilage | Musculoskeletal disease | Osteoarthritis | Osteoarthritis - knee | Physiotherapy | Randomised controlled trial | Rehabilitation

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