Novel therapeutic interventions to increase blood flow to skeletal muscle

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/342115

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Over the past decade it has become clear that the cytokine interleukin (IL)-6 is produced in and released from tissues such as fat and muscle to mediate metabolic processes. In this respect, it acts in a hormone like manner. During this period it has also become apparent that the hormone insulin increases blood flow to skeletal muscle. There is emerging evidence that IL-6 plays a role, not only in metabolic and signalling processes within skeletal muscle, but also in blood flow. This project will determine whether the cytokine IL-6 is a viable therapeutic target in the treatment of blood flow disorders in patients with type 2 diabetes. This has major ramifications since type 2 diabetes has reached pandemic levels in Australia and is estimated to cost the community approximately 800 million dollars per year.

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2007

Funding Scheme: NHMRC Project Grants

Funding Amount: $360,750.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arterioles | blood flow | cell signalling | diabetes | insulin resistance | obesity | type 2 diabetes | vascular disease

Related Links