New technologies for hierarchial shotgun sequencing of recalcitrant and repetitive DNA

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/311213

Funding Status
Closed

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Funded Activity Summary

Many repetitive regions of genomes are difficult to sequence and to assemble. �Sequencing Aided by Mutation� (SAM) is a new sequencing technology, which overcomes many of the difficulties that hinder current sequencing methods. SAM involves forming randomly mutated copies of the target DNA. These copies can then be sequenced and new mathematical tools permit the original target sequence to be revealed from the mutant copies. Here the technology will be developed to aid sequencing of long repetitive DNA fragments in genomes.

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2006

Funding Scheme: NHMRC Development Grants

Funding Amount: $79,750.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Molecular Engineering of Nucleic Acids and Proteins

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Bioinformatics | DNA sequencing | Human genome project

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