A phenomic and genomic approach to identifying pharmaceutical targets for the amelioration of hematopoietic deficit

Funding Activity

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Funded Activity Summary

Mice and humans are genetically and physiologically similar, and are afflicted by many of the same diseases. By introducing random DNA mutations into the germline, mice with diseaseassociated characteristics can be generated, allowing the subsequent identification of genes involved in particular human disease processes. This project will utilise cutting-edge genetic technologies to discover genes that regulate production of the body�s principal blood clotting agents: platelets. This is of particular clinical and commercial importance since a reduction in platelet numbers is the life-threatening result of congenital and autoimmune diseases, viral infections (e.g. HIV) and cancer chemotherapy.

Funded Activity Details

Start Date: 01-01-2004

End Date: 01-01-2004

Funding Scheme: Early Career Fellowships

Funding Amount: $87,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetics

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

Biotechnology | Clinical Sciences | Genetics