Enterovirus 71 in the Asia-Pacific region: reverse genetic approaches to virus surveillance and vaccine development.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/303111

Funding Status
Closed

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Funded Activity Summary

In this research the team will use advanced biotechnological techniques to study the distribution and virulence markers of an important emerging infectious disease, enterovirus 71 encephalitis, in the Asia-Pacific region. The knowledge and technical advances derived from this study will be shared with neighbouring countries in order to conduct sensitive surveillance for this infection throughout the region. The study's other major aim is to use cutting-edge biotechnological techniques to develop a genetically defined, live attenuated vaccine strain. Candidate vaccine strains will be tested for their effectiveness in both cell culture-based and animal models.

Funded Activity Details

Start Date: 01-01-2004

End Date: 01-01-2009

Funding Scheme: NHMRC Strategic Awards

Funding Amount: $690,833.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied immunology (incl. antibody engineering xenotransplantation and t-cell therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Enterovirus 71 encephalitis | Molecular epidemiology | Molecular genetics of viral virulence | Reverse genetics of RNA viruses

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