The importance of ADAMTS proteases in ovulation and fertility.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/299063

Funding Status
Closed

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Funded Activity Summary

In the ovary eggs are matured within a specialised organ called a follicle. Female fertility is dependent on the efficient release of eggs from the follicle as well as transport of the egg to the site of fertilization. During these processes the egg is encased within a mucous-like cushion made of cells, proteins and complex carbohydrates. This cushion or matrix plays an active role in egg release, transport and fertilization. Proper formation of this cushion just before egg release is therefore essential for efficient female fertility. This project examines the role of newly identified proteins and protease enzymes that are involved in the formation and function of the matrix cushion around eggs. This has important implications for the causes of infertility in women as well as improving the efficacy of IVF techniques.

Funded Activity Details

Start Date: 01-01-2004

End Date: 01-01-2006

Funding Scheme: NHMRC Project Grants

Funding Amount: $205,500.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anovulation | extracellular matrix | fertilization | in vitro fertilization | infertility | ovary | ovulation | protease

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