Development of modified IGF-binding proteins as novel anti-cancer chemotherapeutics

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/298975

Funding Status
Closed

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Funded Activity Summary

We propose to enhance the effectiveness of current anti-cancer treatments by co-administering a protein to sequester growth factors that promote the resistance of cancer cells to chemotherapy. We aim to achieve improved destruction of breast and colorectal cancers but with reduced adverse side effects. Our in vitro data show the effectiveness of this novel co-therapeutic which is a modified form of a natural carrier protein for these growth factors. This application seeks funding to enable proof of concept in vivo in order to attract commercial funding for clinical trials.

Funded Activity Details

Start Date: 01-01-2005

End Date: 01-01-2005

Funding Scheme: NHMRC Development Grants

Funding Amount: $77,375.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Oncology And Carcinogenesis

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Breast Cancer | Cell proliferation | Growth factor | IGF | Prostate Cancer

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