Studies on the role of the MIP-3beta/SLC system in the priming phase of the cytotoxic T lymphocyte response.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/250359

Funding Status
Closed

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Funded Activity Summary

Generation of cytotoxic T cells (CTLs) is important for defence against viruses and cancer cells. However, when activated inappropriately, CTLs can contribute to diseases such as diabetes as well as transplant rejection. We intend to study the role of several recently-discovered proteins in this process. The outcome of this work may lead to the development of molecules that control CTL generation more specifically than existing therapeutics. Such inhibitors would potentially be useful in the treatment of a range of human diseases.

Funded Activity Details

Start Date: 01-01-2003

End Date: 01-01-2005

Funding Scheme: NHMRC Project Grants

Funding Amount: $425,250.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical chemistry (incl. diagnostics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

EAE | chemokine | cytotoxicity | inflammation | multiple sclerosis | transplantation

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