Structural studies of the GABA receptor

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/247901

Funding Status
Closed

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Funded Activity Summary

This proposal concerns the biochemical investigation of a protein called GABA receptor which is a known target for various anti-anxiety drugs (anxiolytics), anti-convulsants, sedatives, depressants, anti-epilespy drugs, alcohol and anaesthetics. This work is expected to lead to the determination of the three-dimensional shape of the protein which will provide essential information about how the protein works and lay the foundation for the design and development of new drugs to control epilepsy, act as general anaesthetics, relieve anxiety and induce sleep.

Funded Activity Details

Start Date: 01-01-2003

End Date: 01-01-2007

Funding Scheme: NHMRC Project Grants

Funding Amount: $854,000.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Drug design | Ion channels | Membrane protein | Neurological diseases | Neuropharmacology | Neurotransmission | Protein structure | X-ray crystallography

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